The Agents theme was introduced in 2008 and later re-branded as Agents 2.0 in 2009. The story line and sets where based on an elite team of secret agents using high-powered technology to thwart the plans of an international crime syndicate led by Dr. Inferno. The Agents theme was inspired by James Bond as well as action-packed spy movies. Each Agent set featured a short comic strip on the box showing the background to that set's action.
The Agents was a replacement of the Alpha Team theme. It was discontinued in 2009 and sort of replaced by a similar theme in 2014 called Ultra Agents.