In 2000, LEGO released 13 Basic sets across 2 subthemes, all of these sets have been retired. Subthemes for that year included Mosaic and Seasonal. For that year, the total price of all retail sets cost $90, today those sets are valued around $2,782, a growth of 2993%.
Most valuable 2000 LEGO Basic set
3443 LEGO Mosaic $2,537.40
Most owned 2000 Basic set
2250 Advent Calendar
13 sets

2155 Water-Plane

Theme Basic
Year 2000
Pieces 18
Availability Retired
2155 LEGO Water-Plane
promotional
Value $10.50
Annual growth 8.9%

2156 Racer

Theme Basic
Year 2000
Pieces 17
Availability Retired
2156 LEGO Racer
promotional
Value $13.18
Annual growth 9.0%

2157 Speed Boat

Theme Basic
Year 2000
Pieces 16
Availability Retired
2157 LEGO Speed Boat
promotional
Value $7.06
Annual growth 9.7%

2158 Copter

Theme Basic
Year 2000
Pieces 10
Availability Retired
2158 LEGO Copter
promotional
Value $13.94
Annual growth 9.1%

2250 Advent Calendar

Theme / Subtheme Basic / Seasonal
Year 2000
Pieces 240
Availability Retired
2250 LEGO Advent Calendar
Retail $19.99
Value $45.00
Growth  +125.1%
Annual growth 6.6%

2707 Glider

Theme Basic
Year 2000
Pieces 9
Availability Retired
2707 LEGO Glider
promotional
Value $2.18
Annual growth 3.2%

2708 Aircraft

Theme Basic
Year 2000
Pieces 12
Availability Retired
2708 LEGO Aircraft
promotional
Value $2.18
Annual growth 9.9%

2709 Snowmobile

Theme Basic
Year 2000
Pieces 8
Availability Retired
2709 LEGO Snowmobile
promotional
Value $2.54
Annual growth 1.9%

2710 Helicopter

Theme Basic
Year 2000
Pieces 8
Availability Retired
2710 LEGO Helicopter
promotional
Value $2.23
Annual growth 3.3%

2722 Ship

Theme Basic
Year 2000
Pieces 12
Availability Retired
2722 LEGO Ship
promotional
Value $2.98
Annual growth 4.5%

3443 LEGO Mosaic

Theme / Subtheme Basic / Mosaic
Year 2000
Pieces 2,427
Availability Retired
3443 LEGO Mosaic
Retail $29.99
Value $2,537.40
Growth  +8360.8%
Annual growth 16.1%

4122 Basic Building Set

Theme Basic
Year 2000
Pieces 201
Availability Retired
4122 LEGO Basic Building Set
Retail $19.99
Value $30.83
Growth  +54.2%
Annual growth 3.0%

4249 Suitcase Set

Theme Basic
Year 2000
Pieces / Minifigs 256 / 1
Availability Retired
4249 LEGO Suitcase Set
Retail $19.99
Value $112.29
Growth  +461.7%
Annual growth 7.4%