In 2000, LEGO released 13 Basic sets across 2 subthemes, all of these sets have been retired. Subthemes for that year included Mosaic and Seasonal. For that year, the total price of all retail sets cost $90, today those sets are valued around $808, a growth of 798%.
Most valuable 2000 LEGO Basic set
3443 LEGO Mosaic $500.00
Most owned 2000 Basic set
2250 Advent Calendar
13 sets

2155 Water-Plane

Theme Basic
Year 2000
Pieces 18
Availability Retired
2155 LEGO Water-Plane
promotional
Value $13.34
Annual growth 8.8%

2156 Racer

Theme Basic
Year 2000
Pieces 17
Availability Retired
2156 LEGO Racer
promotional
Value $14.35
Annual growth 7.4%

2157 Speed Boat

Theme Basic
Year 2000
Pieces 16
Availability Retired
2157 LEGO Speed Boat
promotional
Value $10.51
Annual growth 11.3%

2158 Copter

Theme Basic
Year 2000
Pieces 10
Availability Retired
2158 LEGO Copter
promotional
Value $16.00
Annual growth 10.8%

2250 Advent Calendar

Theme / Subtheme Basic / Seasonal
Year 2000
Pieces 240
Availability Retired
2250 LEGO Advent Calendar
Retail $19.99
Value $40.50
Growth  +102.6%
Annual growth 7.7%

2707 Glider

Theme Basic
Year 2000
Pieces 9
Availability Retired
2707 LEGO Glider
promotional
Value $2.26
Annual growth 3.2%

2708 Aircraft

Theme Basic
Year 2000
Pieces 12
Availability Retired
2708 LEGO Aircraft
promotional
Value $2.26
Annual growth 3.2%

2709 Snowmobile

Theme Basic
Year 2000
Pieces 8
Availability Retired
2709 LEGO Snowmobile
promotional
Value $2.63
Annual growth 2.1%

2710 Helicopter

Theme Basic
Year 2000
Pieces 8
Availability Retired
2710 LEGO Helicopter
promotional
Value $2.31
Annual growth 3.3%

2722 Ship

Theme Basic
Year 2000
Pieces 12
Availability Retired
2722 LEGO Ship
promotional
Value $3.12
Annual growth 4.5%

3443 LEGO Mosaic

Theme / Subtheme Basic / Mosaic
Year 2000
Pieces 2,427
Availability Retired
3443 LEGO Mosaic
Retail $29.99
Value $500.00
Growth  +1567.2%
Annual growth 11.4%

4122 Basic Building Set

Theme Basic
Year 2000
Pieces 201
Availability Retired
4122 LEGO Basic Building Set
Retail $19.99
Value $31.56
Growth  +57.9%
Annual growth 2.9%

4249 Suitcase Set

Theme Basic
Year 2000
Pieces / Minifigs 256 / 1
Availability Retired
4249 LEGO Suitcase Set
Retail $19.99
Value $168.99
Growth  +745.4%
Annual growth 8.1%