In 2008, LEGO released 4 Architecture sets across 2 subthemes, all of these sets have been retired. Subthemes for that year included Brickstructures and Landmark Series. For that year, the total price of all retail sets cost $100, today those sets are valued around $2,593, a growth of 2494%.
Most valuable 2008 LEGO Architecture set
19710 Sears Tower $1,185.99
Largest 2008 LEGO Architecture set
19720 John Hancock Center 69 pieces
Most owned 2008 Architecture set
21000 Sears Tower
4 sets

19710 Sears Tower

Theme / Subtheme Architecture / Brickstructures
Year 2008
Pieces 68
Availability Retired
19710 LEGO Architecture Brickstructures Sears Tower
Retail $29.99
Value $1,185.99
Growth  +3854.6%
Annual growth 12.7%

19720 John Hancock Center

Theme / Subtheme Architecture / Brickstructures
Year 2008
Pieces 69
Availability Retired
19720 LEGO Architecture Brickstructures John Hancock Center
Retail $29.99
Value $1,049.82
Growth  +3400.6%
Annual growth 13.5%

21000 Sears Tower

Theme / Subtheme Architecture / Landmark Series
Year 2008
Pieces 69
Availability Retired
21000 LEGO Architecture Sears Tower
Retail $19.99
Value $156.80
Growth  +684.4%
Annual growth 14.9%

21001 John Hancock Center

Theme / Subtheme Architecture / Landmark Series
Year 2008
Pieces 69
Availability Retired
21001 LEGO Architecture John Hancock Center
Retail $19.99
Value $200.27
Growth  +901.9%
Annual growth 17.0%