Spider-Man 2 is a subtheme of Spider-Man introduced in 2004 and currently consists of 4 sets. All sets were released in 2004. As of today, the average annual growth of sets in Spider-Man Spider-Man 2 is approximately 8.7% per year.
The LEGO Spider-Man / Spider-Man 2 theme from 2004 was a subtheme based on Spider-Man 2, the film starring Tobey Maguire as Peter Parker. Released under the broader LEGO Spider-Man theme, these sets recreated key scenes from the movie, with Spider-Man, Doctor Octopus and other characters in builds taken from the film.
Notable sets included 4855 Spider-Man's Train Rescue, which depicted the fight between Spider-Man and Doc Ock on a runaway train, and 4853 Spider-Man's Street Chase, capturing a high-speed pursuit. These sets had minifigures of Spider-Man, Doc Ock, and supporting characters, along with vehicles and city-based builds inspired by the film's setting. The subtheme was part of LEGO's early Marvel-related sets before the LEGO Super Heroes theme launched in 2012.