In 2010, LEGO released 4 Duplo Building Sets sets, all of these sets have been retired. For that year, the total price of all retail sets cost $140, today those sets are valued around $491, a growth of 251%.
Most valuable 2010 LEGO Duplo Building Sets set
5507 Duplo Deluxe Brick Box $258.78
Largest 2010 LEGO Duplo Building Sets set
5511 XXL Box 201 pieces
4 sets

5506 Duplo Large Brick Box

Theme / Subtheme Duplo / Building Sets
Year 2010
Pieces / Duplo figures 71 / 1
Availability Retired
5506 LEGO Duplo Large Brick Box
Retail $29.99
Value $70.57
Growth  +135.3%
Annual growth 7.0%

5507 Duplo Deluxe Brick Box

Theme / Subtheme Duplo / Building Sets
Year 2010
Pieces / Duplo figures 102 / 2
Availability Retired
5507 LEGO Duplo Deluxe Brick Box
Retail $49.99
Value $258.78
Growth  +417.7%
Annual growth 6.0%

5511 XXL Box

Theme / Subtheme Duplo / Building Sets
Year 2010
Pieces 201
Availability Retired
5511 LEGO Duplo XXL Box
Retail $29.99
Value $69.33
Growth  +131.2%
Annual growth 7.3%

5548 Duplo Building Fun

Theme / Subtheme Duplo / Building Sets
Year 2010
Pieces 81
Availability Retired
5548 LEGO Duplo Building Fun
Retail $29.99
Value $92.45
Growth  +208.3%
Annual growth 5.7%