In 2001, LEGO released 3 Mindstorms sets across 2 subthemes, all of these sets have been retired. Subthemes for that year included 1 and 2. For that year, the total price of all retail sets cost $280, today those sets are valued around $589, a growth of 110%.
Most valuable 2001 LEGO Mindstorms set
3804 Robotics Invention System V2.0 $429.47
Highest growth 2001 Mindstorms set
3805 Robotics Invention System Upgrade Kit +307.60%
3 sets

3800 Ultimate Builders Set

Theme / Subtheme Mindstorms / 1
Year 2001
Pieces 321
Availability Retired
3800 LEGO Mindstorms Ultimate Builders Set
Retail $59.99
Value $78.13
Growth  +30.2%
Annual growth 2.5%

3804 Robotics Invention System V2.0

Theme / Subtheme Mindstorms / 2
Year 2001
Pieces 717
Availability Retired
3804 LEGO Mindstorms Robotics Invention System V2.0
Retail $199.99
Value $429.47
Growth  +114.7%
Annual growth 3.2%

3805 Robotics Invention System Upgrade Kit

Theme / Subtheme Mindstorms / 1
Year 2001
Pieces 1
Availability Retired
3805 LEGO Mindstorms Robotics Invention System Upgrade Kit
Retail $19.99
Value $81.48
Growth  +307.6%
Annual growth 5.8%