In 2021, LEGO released 17 BrickHeadz sets across 6 subthemes, all of these sets have been retired. Subthemes for that year included Disney, Minions The Rise of Gru, Ninjago, Pets, Seasonal, and Wizarding World. For that year, the total price of all retail sets cost $305, today those sets are valued around $466, a growth of 53%.
Most valuable 2021 LEGO BrickHeadz set
40480 Ginger Tabby $44.95
Largest 2021 LEGO BrickHeadz set
40495 Harry, Hermione, Ron & Hagrid 466 pieces
17 sets

40420 Gru, Stuart and Otto

Theme / Subtheme BrickHeadz / Minions The Rise of Gru
Year 2021
Pieces 244
Availability Retired
40420 LEGO BrickHeadz Minions The Rise of Gru Gru, Stuart and Otto
Retail $19.99
Value $40.00
Growth  +100.1%
Annual growth 13.4%

40421 Belle Bottom, Kevin and Bob

Theme / Subtheme BrickHeadz / Minions The Rise of Gru
Year 2021
Pieces 309
Availability Retired
40421 LEGO BrickHeadz Minions The Rise of Gru Belle Bottom, Kevin and Bob
Retail $19.99
Value $22.33
Growth  +11.7%
Annual growth 5.6%

40440 German Shepherd

Theme / Subtheme BrickHeadz / Pets
Year 2021
Pieces 247
Availability Retired
40440 LEGO BrickHeadz Pets German Shepherd
Retail $14.99
Value $19.59
Growth  +30.7%
Annual growth 6.6%

40441 Shorthair Cats

Theme / Subtheme BrickHeadz / Pets
Year 2021
Pieces 250
Availability Retired
40441 LEGO BrickHeadz Pets Shorthair Cats
Retail $14.99
Value $31.86
Growth  +112.5%
Annual growth 9.0%

40442 Goldfish

Theme / Subtheme BrickHeadz / Pets
Year 2021
Pieces 186
Availability Retired
40442 LEGO BrickHeadz Pets Goldfish
Retail $14.99
Value $21.52
Growth  +43.6%
Annual growth 5.5%

40443 Budgie

Theme / Subtheme BrickHeadz / Pets
Year 2021
Pieces 261
Availability Retired
40443 LEGO BrickHeadz Pets Budgie
Retail $14.99
Value $19.98
Growth  +33.3%
Annual growth 6.4%

40466 Chinese New Year Pandas

Theme / Subtheme BrickHeadz / Seasonal
Year 2021
Pieces 249
Availability Retired
40466 LEGO BrickHeadz Chinese New Year Pandas
Retail $19.99
Value $19.95

40476 Daisy Duck

Theme / Subtheme BrickHeadz / Disney
Year 2021
Pieces 110
Availability Retired
40476 LEGO BrickHeadz Disney Daisy Duck
Retail $9.99
Value $14.98
Growth  +49.9%
Annual growth 7.8%

40477 Scrooge McDuck, Huey, Dewey & Louie

Theme / Subtheme BrickHeadz / Disney
Year 2021
Pieces 340
Availability Retired
40477 LEGO BrickHeadz Disney Scrooge McDuck, Huey, Dewey & Louie
Retail $24.99
Value $27.98
Growth  +12.0%
Annual growth 7.3%

40479 Dalmatian

Theme / Subtheme BrickHeadz / Pets
Year 2021
Pieces 252
Availability Retired
40479 LEGO BrickHeadz Pets Dalmatian
Retail $14.99
Value $18.50
Growth  +23.4%
Annual growth 4.6%

40480 Ginger Tabby

Theme / Subtheme BrickHeadz / Pets
Year 2021
Pieces 269
Availability Retired
40480 LEGO BrickHeadz Pets Ginger Tabby
Retail $14.99
Value $44.95
Growth  +199.9%
Annual growth 20.4%

40481 Cockatiel

Theme / Subtheme BrickHeadz / Pets
Year 2021
Pieces 219
Availability Retired
40481 LEGO BrickHeadz Pets Cockatiel
Retail $14.99
Value $28.68
Growth  +91.3%
Annual growth 9.2%

40482 Hamster

Theme / Subtheme BrickHeadz / Pets
Year 2021
Pieces 243
Availability Retired
40482 LEGO BrickHeadz Pets Hamster
Retail $14.99
Value $31.55
Growth  +110.5%
Annual growth 11.7%

40490 Ninjago 10

Theme / Subtheme BrickHeadz / Ninjago
Year 2021
Pieces 406
Availability Retired
40490 LEGO BrickHeadz Ninjago 10
Retail $29.99
Value $34.59
Growth  +15.3%
Annual growth 4.5%

40492 La Catrina

Theme / Subtheme BrickHeadz / Seasonal
Year 2021
Pieces 141
Availability Retired
40492 LEGO BrickHeadz La Catrina
Retail $9.99
Value $22.98
Growth  +130.0%
Annual growth 22.9%

40495 Harry, Hermione, Ron & Hagrid

Theme / Subtheme BrickHeadz / Wizarding World
Year 2021
Pieces 466
Availability Retired
40495 LEGO BrickHeadz Wizarding World Harry, Hermione, Ron & Hagrid
Retail $24.99
Value $37.04
Growth  +48.2%
Annual growth 16.8%

40496 Voldemort, Nagini & Bellatrix

Theme / Subtheme BrickHeadz / Wizarding World
Year 2021
Pieces 344
Availability Retired
40496 LEGO BrickHeadz Wizarding World Voldemort, Nagini & Bellatrix
Retail $24.99
Value $29.97
Growth  +19.9%
Annual growth 5.4%